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Article

Blood DNA methylation and breast cancer risk: a prospective nested case-control study.

EBioMedicine - 1 Jul 2026

Rodriguez Juan, Grassmann Felix, Kaukonen Damien, Hägg Sara, Humphreys Keith, Eriksson Mikael, Zhang Yuqi, Morawitz Katharina, Gabrielson Marike, Hall Per, Czene Kamila

Abstract excerpt

BACKGROUND: Blood tests that predict breast cancer (BC) risk before diagnosis could complement mammography screening. Whole-blood DNA methylation is stable and may capture early systemic changes related to tumour development. METHODS: We conducted a prospective matched case-control study nested within Sweden's mammography screening programme, profiling whole-blood DNA methylation on the Illumina MethylationEPIC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42349257
DOI: 10.1016/j.ebiom.2026.106352
PMCID: PMC13320414

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