Article
DNA methylation array analysis identifies breast cancer associated RPTOR, MGRN1 and RAPSN hypomethylation in peripheral blood DNA.
Oncotarget - 27 Sept 2016
Tang Qiuqiong, Holland-Letz Tim, Slynko Alla, Cuk Katarina, Marme Frederik, Schott Sarah, Heil Jörg, Qu Bin, Golatta Michael, Bewerunge-Hudler Melanie, Sutter Christian, Surowy Harald, Wappenschmidt Barbara, Schmutzler Rita, Hoth Markus, Bugert Peter, Bartram Claus R, Sohn Christof, Schneeweiss Andreas, Yang Rongxi, Burwinkel Barbara
Abstract excerpt
DNA methylation changes in peripheral blood DNA have been shown to be associated with solid tumors. We sought to identify methylation alterations in whole blood DNA that are associated with breast cancer (BC). Epigenome-wide DNA methylation profiling on blood DNA from BC cases and healthy controls was performed by applying Infinium HumanMethylation450K BeadChips. Promising CpG sites were selected and validated in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.