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Homologous Recombination Subpathways: A Tangle to Resolve

2 Aug 2021

Abstract excerpt

Homologous recombination (HR) is an essential pathway for DNA double-strand break (DSB) repair, which can proceed through various subpathways that have distinct elements and genetic outcomes. In this mini-review, we highlight the main features known about HR subpathways operating at DSBs in human cells and the factors regulating subpathway choice. We examine new developments that provide alternative models of...

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PMID: 34408777
DOI: 10.3389/fgene.2021.723847

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