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ATRX and RECQ5 define distinct homologous recombination subpathways

11 Jan 2021

Abstract excerpt

Homologous recombination (HR) is an important DNA double-strand break (DSB) repair pathway that copies sequence information lost at the break site from an undamaged homologous template. This involves the formation of a recombination structure that is processed to restore the original sequence but also harbors the potential for crossover (CO) formation between the participating molecules. Synthesis-dependent...

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PMID: 33431668
DOI: 10.1073/pnas.2010370118

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