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Fast and Efficient Genome Editing of Human FOXP3+ Regulatory T Cells

2 Aug 2021

Abstract excerpt

FOXP3 + regulatory T cells (Tregs) are central for maintaining peripheral tolerance and immune homeostasis. Because of their immunosuppressive characteristics, Tregs are a potential therapeutic target in various diseases such as autoimmunity, transplantation and infectious diseases like COVID-19. Numerous studies are currently exploring the potential of adoptive Treg therapy in different disease settings and...

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Identifiers

PMID: 34408743
DOI: 10.3389/fimmu.2021.655122

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