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Comparing osteonecrosis clinical phenotype, timing, and risk factors in children and young adults treated for acute lymphoblastic leukemia.

Pediatric blood & cancer - 1 Oct 2018

Mogensen Signe Sloth, Harila-Saari Arja, Mäkitie Outi, Myrberg Ida Hed, Niinimäki Riitta, Vestli Anne, Hafsteinsdottir Solveig, Griškevicius Laimonas, Saks Kadri, Hallböök Helene, Retpen Jens, Helt Louise Rold, Toft Nina, Schmiegelow Kjeld, Frandsen Thomas Leth

Abstract excerpt

BACKGROUND: Treatment-related osteonecrosis (ON) is a serious complication of treatment of acute lymphoblastic leukemia (ALL). PROCEDURE: This study included 1,489 patients with ALL, aged 1-45 years, treated according to the Nordic Society of Paediatric Haematology and Oncology ALL2008 protocol, using alternate-week dexamethasone during delayed intensification, with prospective registration of symptomatic ON. We...

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PMID: 29943905
DOI: 10.1002/pbc.27300

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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