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DNA methylation as a mediator of associations between the environment and chronic diseases: A scoping review on application of mediation analysis

12 Aug 2021

Abstract excerpt

DNA methylation (DNAm) is one of the most studied epigenetic modifications. DNAm has emerged as a key biological mechanism and biomarkers to test associations between environmental exposure and outcomes in epidemiological studies. Although previous studies have focused on associations between DNAm and either exposure/outcomes, it is useful to test for mediation of the association between exposure and outcome by...

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PMID: 34384035
DOI: 10.1080/15592294.2021.1959736

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