Article
Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships.
Human genetics - 1 Oct 2012
Cortessis Victoria K, Thomas Duncan C, Levine A Joan, Breton Carrie V, Mack Thomas M, Siegmund Kimberly D, Haile Robert W, Laird Peter W
Abstract excerpt
Changes in epigenetic marks such as DNA methylation and histone acetylation are associated with a broad range of disease traits, including cancer, asthma, metabolic disorders, and various reproductive conditions. It seems plausible that changes in epigenetic state may be induced by environmental exposures such as malnutrition, tobacco smoke, air pollutants, metals, organic chemicals, other sources of oxidative...
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