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Article

SH3BGRL3 binds to myosin 1c in a calcium dependent manner and modulates migration in the MDA-MB-231 cell line

11 Aug 2021

Abstract excerpt

Abstract Background The humanSH3 domain Binding Glutamic acid Rich Like 3(SH3BGRL3) gene is highly conserved in phylogeny and widely expressed in human tissues. However, its function is largely undetermined. The protein was found to be overexpressed in several tumors, and recent work suggested a possible relationship with EGFR family members. We aimed at further highlighting on these issues and investigated...

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PMID: 34380438
DOI: 10.1186/s12860-021-00379-1

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