Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BAFF signaling in health and disease

1 Aug 2021

Abstract excerpt

BAFF is a critical cytokine supporting the survival of mature naïve B cells, acting through the BAFFR receptor. Recent studies show that BAFF and BAFFR are also required for the survival of memory B cells, autoimmune B cells as well as malignant chronic lymphocytic leukaemia (CLL) cells. BAFFR cooperates with other receptors, notably the B cell antigen receptor (BCR), a process which is critical for the expansion...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Lymphocytic Leukemia Research
Share to Cytokine Signaling Pathways and Interactions
Share to NF-κB Signaling Pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34352467
DOI: 10.1016/j.coi.2021.06.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BAFF signaling in health and diseasePMID 34352467Read ↗

A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling.Semantic proximity Read ↗

TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor.Semantic proximity Read ↗

An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway.Semantic proximity Read ↗

Thyroid hormone induces B cells abnormal differentiation via overexpression of B cell-activating factorSemantic proximity Read ↗

Integrated B Cell, Toll-like, and BAFF Receptor Signals Promote Autoantibody Production by Transitional B CellsSemantic proximity Read ↗

A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.Semantic proximity Read ↗

Polymorphonuclear Myeloid-Derived Suppressor Cells Promote Inflammation Progression of Rheumatoid Arthritis by Inducing Age-Associated B Cell Proliferation and Differentiation via the BAFF-Mediated SYK-ERK1/2 PathwaySemantic proximity Read ↗

BAFF-driven autoimmunity requires CD19 expression.Semantic proximity Read ↗

The SLAM family receptors: Potential therapeutic targets for inflammatory and autoimmune diseasesSemantic proximity Read ↗

The path less traveled: the non-canonical NF-κB pathway in systemic lupus erythematosusSemantic proximity Read ↗

The B7 family of immune-regulatory ligands.Semantic proximity Read ↗

TACItly changing tunes: farewell to a yin and yang of BAFF receptor and TACI in humoral immunity? New genetic defects in common variable immunodeficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.