The path less traveled: the non-canonical NF-κB pathway in systemic lupus erythematosus

Abstract excerpt

Systemic Lupus Erythematosus (SLE) is an autoimmune disease in which autoantibody production and cytokine dysregulation leads to systemic organ and tissue damage that can result in mortality. Although various environmental, hormonal, and genetic factors can contribute to disease pathogenesis, the cause of this disease is not known. Traditional treatment for this disease is centered around limiting inflammation...

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