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Article

A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling.

The Journal of experimental medicine - 22 Nov 2010

Hildebrand Joanne M, Luo Zhenghua, Manske Michelle K, Price-Troska Tammy, Ziesmer Steven C, Lin Wai, Hostager Bruce S, Slager Susan L, Witzig Thomas E, Ansell Stephen M, Cerhan James R, Bishop Gail A, Novak Anne J

Abstract excerpt

The cytokine B cell activating factor (BAFF) and its receptor, BAFF receptor (BAFF-R), modulate signaling cascades critical for B cell development and survival. We identified a novel mutation in TNFRSF13C, the gene encoding human BAFF-R, that is present in both tumor and germline tissue from a su...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to TNF Receptor-Associated Factor 6

Source

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Identifiers

PMID: 21041452
DOI: 10.1084/jem.20100857
PMCID: PMC2989778

Genes

TRAF6
TRAF3
TRAF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21041452-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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