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Article

cGAS-STING effectively restricts murine norovirus infection but antagonizes the antiviral action of N-terminus of RIG-I in mouse macrophages

1 Jan 2021

Abstract excerpt

Although cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling has been well recognized in defending DNA viruses, the role of cGAS-STING signaling in regulating infection of RNA viruses remains largely elusive. Noroviruses, as single-stranded RNA viruses, are the main causative agents of acute viral gastroenteritis worldwide. This study comprehensively investigated the role of cGAS-STING...

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PMID: 34347572
DOI: 10.1080/19490976.2021.1959839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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