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Surgical management of BRCA pathogenic variant carriers with breast cancer: a recent literature review and current state of the art.

Minerva surgery - 1 Dec 2021

Terribile Daniela A, Mason Elena J, Murando Federica, DI Leone Alba, Sanchez Alejandro M, Scardina Lorenzo, Magno Stefano, Franco Antonio, D'Archi Sabatino, Natale Maria, Lucci Cordisco Emanuela, Masetti Riccardo, Franceschini Gianluca

Abstract excerpt

Surgical management of breast cancer patients carrying pathogenic variants (PV) on breast cancer genes (BRCA) 1 and 2 has changed throughout the last decade due to growing availability of genetic testing, and has shifted towards the diffusion of bilateral mastectomy. Today's scenario however is in further evolution because of emerging data that suggest a personalized modulation of treatment. In this work we aimed...

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PMID: 34338470
DOI: 10.23736/S2724-5691.21.09009-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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