Article
Breast cancer treatment in mutation carriers: surgical treatment.
Minerva ginecologica - 1 Oct 2016
Biglia Nicoletta, D'Alonzo Marta, Sgro Luca G, Tomasi Cont Nicoletta, Bounous Valentina, Robba Elisabetta
Abstract excerpt
The surgical option which should be reserved for patients with BRCA1/2 mutation and breast cancer diagnosis is still debated. Several aspects should be considered before the surgical decision-making: the risk of ipsilateral breast recurrence (IBR), the risk of contralateral breast cancer (CBC), the potential survival benefit of prophylactic mastectomy, and the possible risk factors that could either increase or...
Topics
- BRCA1 Protein
- BRCA2 Protein
- Breast Neoplasms
- Chemotherapy, Adjuvant
- Female
- Humans
- Mammaplasty
- Mastectomy
- Mastectomy, Subcutaneous
- Mutation
- Neoplasm Recurrence, Local