Article
Surgical Management of Hereditary Breast Cancer.
Genes - 31 Aug 2021
Berger Elizabeth R, Golshan Mehra
Abstract excerpt
The identification that breast cancer is hereditary was first described in the nineteenth century. With the identification of the BRCA1 and BRCA 2 breast/ovarian cancer susceptibility genes in the mid-1990s and the introduction of genetic testing, significant advancements have been made in tailoring surveillance, guiding decisions on medical or surgical risk reduction and cancer treatments for genetic variant...
Topics
- Antineoplastic Agents
- BRCA1 Protein
- BRCA2 Protein
- Breast Neoplasms
- Chemoprevention
- Female
- Genetic Predisposition to Disease
- Genetic Testing
- Hereditary Breast and Ovarian Cancer Syndrome
- Heterozygote
- Humans