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Breast Conserving Surgery for BRCA Mutation Carriers-A Systematic Review.

Clinical breast cancer - 1 Jun 2020

Co Michael, Liu Thomas, Leung Jason, Li Chung Hin, Tse Theo, Wong Michael, Kwong Ava

Abstract excerpt

Similar to mastectomy, breast conserving surgery (BCS) is currently the reference standard of surgical treatment of sporadic breast cancer in patients. However, its oncologic safety for BRCA mutation carriers has remained controversial. Thus, we conducted a systematic review to critically evaluate the best evidence from reported studies. A comprehensive search was performed of the Medline, EMBASE, CINAHL, and...

Topics

BRCA1 Protein
BRCA2 Protein
Breast Neoplasms
Clinical Decision-Making
Female
Humans
Mastectomy, Segmental
Mutation
Neoplasm Recurrence, Local
Patient Preference
Risk Assessment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Survival Rate

Treatment Outcome

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Identifiers

PMID: 32144082
DOI: 10.1016/j.clbc.2019.07.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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