Article
Management options after prophylactic surgeries in women with BRCA mutations: a review.
Cancer control : journal of the Moffitt Cancer Center - 1 Oct 2007
Allain Dawn C, Sweet Kevin, Agnese Doreen M
Abstract excerpt
BACKGROUND: Although breast cancer is relatively common, only about 5% of cases are due to inheritance of highly penetrant cancer susceptibility genes. The majority of these are caused by mutations in the BRCA1 and BRCA2 genes, which are also associated with an increased risk of ovarian cancer. Increased surveillance, chemoprevention, and prophylactic surgeries are standard options for the effective medical...
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