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Surgical management of BRCA-mutation carriers: A single institution experience.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Aug 2022

Gentile Damiano, Losurdo Agnese, Sagona Andrea, Zuradelli Monica, Gatzemeier Wolfgang, Barbieri Erika, Testori Alberto, Errico Valentina, Bianchi Paolo, Biondi Ersilia, Torrisi Rosalba, Santoro Armando, Tinterri Corrado

Abstract excerpt

INTRODUCTION: The optimal surgical management of BRCA-mutation carriers remains a subject of debate. To evaluate the appropriateness of breast cancer (BC) treatment, the oncological outcomes of BRCA-mutation carriers treated either with breast-conserving therapy (BCT) or mastectomy were compared. Additionally, the role of bilateral salpingo-oophorectomy (BSO) and potential independent predictive factors for BC...

Topics

Adult
Breast Neoplasms
Female
Genes, BRCA2
Humans
Mastectomy
Mutation
Retrospective Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35534308
DOI: 10.1016/j.ejso.2022.04.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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