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Article

Influence of germline test results on surgical decision making in women with invasive breast cancer.

Cancer genetics - 1 Aug 2022

Vargason Ashlee B, Turner Clesson E, Shriver Craig D, Ellsworth Rachel E

Abstract excerpt

BACKGROUND: While therapeutic mastectomy with contralateral prophylactic mastectomy (TM+CPM) and/or bilateral salpingo-oophorectomy (BSO) are recommended for women with pathogenic variants (PV) in some cancer predisposition genes, evidence for the utility of these surgeries for women with PV in other genes currently is insufficient. In conjunction, current guidelines recommend that clinical management should not...

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Identifiers

PMID: 35868102
DOI: 10.1016/j.cancergen.2022.07.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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