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Article

The Genetic and Environmental Factors of Primary Membranous Nephropathy: An Overview from China

1 Jan 2018

Abstract excerpt

Background: Primary membranous nephropathy (pMN) is the most common cause of nephrotic syndrome in adults. The discovery of the 2 autoantigens, M-type phospholipase A2 receptor (PLA2R) and thrombospondin type-1 domain-containing 7A (THSD7A), has defined pMN as an autoimmune disease. A remarkable increase in the frequency of pMN in primary glomerular disease was witnessed in China. The genetic and environmental...

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PMID: 29998121
DOI: 10.1159/000487136

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