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SEMA4D Knockdown Attenuates β‐Catenin‐Dependent Tumor Progression in Colorectal Cancer

1 Jan 2021

Abstract excerpt

Semaphorin 4D (SEMA4D), a protein originally demonstrated to regulate the immune system and axonal growth cone collapse in the developing central nervous system, is overexpressed in various human malignancies, including colorectal cancer (CRC). This investigation was undertaken to examine the effects of SEMA4D silencing on the biological properties of the CRC cell line. SW48 cells were transfected with a...

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PMID: 34337054
DOI: 10.1155/2021/8507373

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