Article
Downregulation of S100A4 expression by RNA interference suppresses cell growth and invasion in human colorectal cancer cells
20 Dec 2011
Abstract excerpt
S100A4 protein, a member of the S100 superfamily of calcium-binding proteins, is frequently observed in various types of human cancers, including colorectal cancer (CRC). Our previous investigations have demonstrated that the overexpression of S100A4 is associated with lymph node metastasis and poor prognosis in CRC; however, its biological roles in CRC remain unclear. In the present study, we compared the...
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