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Article

Pre-existing Thyroiditis Ameliorates Papillary Thyroid Cancer: Insights From a New Mouse Model.

Endocrinology - 1 Oct 2021

Pani Fabiana, Yasuda Yoshinori, Di Dalmazi Giulia, Chalan Paulina, Gabrielson Kathleen, Adamo Luigi, Sabini Elena, Mariotti Stefano, Caturegli Patrizio

Abstract excerpt

Papillary thyroid cancer (PTC) often co-occurs with Hashimoto's thyroiditis, an association that has long been reported in clinical studies yet remains controversial. Some studies, in fact, have suggested a protective effect of thyroiditis while others have not. We generated a mouse model where PTC and thyroiditis develop in a predictable manner, combining the oncogenic drive of the BRAFv600E mutation (inducible...

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Source

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Identifiers

PMID: 34331442
DOI: 10.1210/endocr/bqab144
PMCID: PMC8389179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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