Article
T cell exhaustion is associated with the risk of papillary thyroid carcinoma and can be a predictive and sensitive biomarker for diagnosis.
Diagnostic pathology - 31 Aug 2021
Zhu Chumeng, Dai Yuechu, Zhang Hui, Ruan Yanyun, Zhou Yong, Dai Yingjie, Fan Lilong, Jia Tianjun, Lu Hongsheng, Chen Qi
Abstract excerpt
BACKGROUND: The incidence of papillary thyroid carcinoma (PTC) has been steadily increasing over the past decades. Hashimoto's thyroiditis (HT) is the most common autoimmune disease, and is related to the pathogenesis of PTC. Programmed death-1 (PD-1) is currently used for the treatment of PTC, but there are very few studies on the clinical value of PD-1 in the diagnosis and targeted therapy of PTC. METHODS: The...
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