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Article

Gene expression profiling of 19q-loss astrocytomas suggest a specific pattern associated with the better prognosis.

Journal of neuro-oncology - 1 Sept 2021

Otani Ryohei, Mukasa Akitake, Uzuka Takeo, Higuchi Fumi, Matsuda Hadzki, Nomura Masashi, Tanaka Shota, Kim Phyo, Ueki Keisuke

Abstract excerpt

PURPOSE: We previously reported that there was a subgroup of IDH-mutated astrocytomas harboring only 19q-loss showing oligodendroglioma-like morphology and significantly longer overall survival (OS) compared with 19q-intact astrocytomas. The aim of this study was to further explore the biological characteristics of this possible subgroup and obtain insight into the mechanism of their relatively benign clinical...

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Source

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PMID: 34328582
DOI: 10.1007/s11060-021-03816-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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