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Article

IDH-mutated astrocytomas with 19q-loss constitute a subgroup that confers better prognosis.

Cancer science - 1 Jul 2018

Otani Ryohei, Uzuka Takeo, Higuchi Fumi, Matsuda Hadzki, Nomura Masashi, Tanaka Shota, Mukasa Akitake, Ichimura Koichi, Kim Phyo, Ueki Keisuke

Abstract excerpt

IDH-mutant gliomas are classified into astrocytic or oligodendroglial tumors by 1p/19q status in the WHO 2016 classification, with the latter presenting with characteristic morphology and better prognosis in general. However, the morphological and genetic features within each category are varied, and there might be distinguishable subtypes. We analyzed 170 WHO grade II-IV gliomas resected in our institution....

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PMID: 29752851
DOI: 10.1111/cas.13635
PMCID: PMC6029820

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