Article
IDH-Mutant Astrocytoma With Chromosome 19q13 Deletion Manifesting as an Oligodendroglioma-Like Morphology.
Journal of neuropathology and experimental neurology - 22 Feb 2021
Miyake Yohei, Fujii Keita, Nakamaura Taishi, Ikegaya Naoki, Matsushita Yuko, Gobayashi Yuko, Iwashita Hiromichi, Udaka Naoko, Kumagai Jiro, Murata Hidetoshi, Takemoto Yasunori, Yamanaka Shoji, Ichimura Koichi, Tateishi Kensuke, Yamamoto Tetsuya
Abstract excerpt
Partial deletions in chromosomes 1p and 19q are found in a subset of astrocytic tumors; however, it remains unclear how these alterations affect their histological features and prognosis. Herein, we present 3 cases of isocitrate dehydrogenase (IDH)-mutant astrocytoma with chromosome 19q13 deletion. In the first case, the primary tumor harbored an IDH1 mutation with chromosome 1p/19q partial deletions, which...
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