Article
Not all 1p/19q non-codeleted oligodendroglial tumors are astrocytic.
Oncotarget - 4 Oct 2016
Li Yan-Xi, Shi Zhifeng, Aibaidula Abudumijiti, Chen Hong, Tang Qisheng, Li Kay Ka-Wai, Chung Nellie Yuk-Fei, Chan Danny Tat-Ming, Poon Wai Sang, Mao Ying, Wu Jinsong, Zhou Liangfu, Chan Aden Ka-Yin, Ng Ho-Keung
Abstract excerpt
Although 1p/19q codeletion is the genetic hallmark defining oligodendrogliomas, approximately 30-40% of oligodendroglial tumors have intact 1p/19q in the literature and they demonstrate a worse prognosis. This group of 1p/19q intact oligodendroglial tumors is frequently suggested to be astrocytic in nature with TP53 and ATRX mutations but actually remains under-investigated. In the present study, we provided...
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