Article
Chromosome 1p and 19q status and p53 and p16 expression patterns as prognostic indicators of oligodendroglial tumors: a clinicopathological study using fluorescence in situ hybridization.
Neuropathology : official journal of the Japanese Society of Neuropathology - 1 Feb 2007
Jeon Yoon Kyung, Park Kyeongmee, Park Chul Ki, Paek Sun Ha, Jung Hee Won, Park Sung-Hye
Abstract excerpt
To verify the prognostic implications of the statuses of chromosome 1p and 19q and the expressions of p53, p16 and GFAP in oligodendrogliomas, we investigated these parameters and correlated the results with patient outcome. Twenty-seven cases of low-grade oligodendroglioma (LO) and 29 cases of anaplastic oligodendroglioma (AO) were analyzed by FISH for 1p and 19q status and by immunohistochemistry for p53, p16,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.