Article
Contrast enhancement in 1p/19q-codeleted anaplastic oligodendrogliomas is associated with 9p loss, genomic instability, and angiogenic gene expression.
Neuro-oncology - 1 May 2014
Reyes-Botero German, Dehais Caroline, Idbaih Ahmed, Martin-Duverneuil Nadine, Lahutte Marion, Carpentier Catherine, Letouzé Eric, Chinot Olivier, Loiseau Hugues, Honnorat Jerome, Ramirez Carole, Moyal Elisabeth, Figarella-Branger Dominique, Ducray François
Abstract excerpt
BACKGROUND: The aim of this study was to correlate MRI features and molecular characteristics in anaplastic oligodendrogliomas (AOs). METHODS: The MRI characteristics of 50 AO patients enrolled in the French national network for high-grade oligodendroglial tumors were analyzed. The genomic profiles and IDH mutational statuses were assessed using high-resolution single-nucleotide polymorphism arrays and direct...
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