Article
[Development of molecular markers of Mycobacterium tuberculosis rifampicin resistance gene rpoB by PARMS technology].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 25 Jul 2021
Liu Xiaohui, Zu Xiangyang, Wang Zhenzhen, Zhao Pengchao, Gao Lei, Zhao Zhanqin, Xue Yun
Abstract excerpt
The purpose of this study is to provide a simple and reliable genetic typing approach for molecular drug susceptibility test of Mycobacterium tuberculosis, through the developing of fluorescence molecular marker of rifampicin resistance gene rpoB. Eleven fluorescent molecular markers of the rpoB gene were established by using the sequence difference between the amino acid positions 531, 526, 516, 511 and 513 of...
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