Article
Rifampicin resistance mutations in the 81 bp RRDR of rpoB gene in Mycobacterium tuberculosis clinical isolates using Xpert MTB/RIF in Khyber Pakhtunkhwa, Pakistan: a retrospective study.
BMC infectious diseases - 12 Aug 2016
Ullah Irfan, Shah Aamer Ali, Basit Anila, Ali Mazhar, Khan Afsar, Ullah Ubaid, Ihtesham Muhammad, Mehreen Sumaira, Mughal Anita, Javaid Arshad
Abstract excerpt
BACKGROUND: Multi-drug resistant tuberculosis (MDR-TB) is a major public health problem especially in developing countries. World Health Organization (WHO) recommends use of Xpert MTB/RIF assay to simultaneously detecting Mycobacterium tuberculosis (MTB) and rifampicin (RIF) resistance. The primary objective of this study was to determine the frequency of MDR-TB in patients suspected to have drug resistance in...
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