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[Evaluation of pyrosequencing for the detection of rpoB gene mutation in Mycobacterium tuberculosis].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Feb 2008

Zheng Rui-juan, Wang Jie, Qin Lian-hua, Lu Jun-mei, Hu Zhong-yi

Abstract excerpt

OBJECTIVE: To detect the mutations of rpoB gene in Mycobacterium tuberculosis by pyrosequencing and to evaluate the values on detection of rifampin resistance in clinical isolates. METHODS: Using the new technology of pyrosequencing, the mutations in the rifampin resistance determining region (RRDR) of rpoB gene were analyzed. The results were compared with those obtained from methods of the absolute...

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PMID: 18642656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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