Article
[Conventional and molecular diagnosis in a group of patients with drug-resistant tuberculosis].
Pneumologia (Bucharest, Romania) - 1 Jan 2000
Mindru Roxana, Spînu Victor, Popa Cristina, Botezatu Elena, Spătaru Ruxandra
Abstract excerpt
Worldwide, although the incidence of the sensitive/susceptible tuberculosis diminished, the number of drug resistant tuberculosis is growing. The bacteriological diagnosis, genetic and phenotypic, becomes essential for the epidemic control. The resistance appears as a phenotypic expression of mutations from M. tuberculosis genome. The mutations that appear for Rifampicin are in region rpoB, for Isoniazid in...
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