Article
Formin 3 directs dendritic architecture via microtubule regulation and is required for somatosensory nociceptive behavior.
Development (Cambridge, England) - 15 Aug 2021
Das Ravi, Bhattacharjee Shatabdi, Letcher Jamin M, Harris Jenna M, Nanda Sumit, Foldi Istvan, Lottes Erin N, Bobo Hansley M, Grantier Benjamin D, Mihály József, Ascoli Giorgio A, Cox Daniel N
Abstract excerpt
Dendrite shape impacts functional connectivity and is mediated by organization and dynamics of cytoskeletal fibers. Identifying the molecular factors that regulate dendritic cytoskeletal architecture is therefore important in understanding the mechanistic links between cytoskeletal organization and neuronal function. We identified Formin 3 (Form3) as an essential regulator of cytoskeletal architecture in...
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