Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeted capture sequencing identifies genetic variations of GRK4 and RDH8 in Han Chinese with essential hypertension in Xinjiang.

PloS one - 1 Jan 2021

Jiang Wenxi, Wang Xizi, Li Ronghui, Wang Panpan, Shan Guangle, Jia Xiaodong, Gu Mingliang

Abstract excerpt

Essential hypertension is a common cardiovascular disease with complex etiology, closely related to genetic and environmental factors. The pathogenesis of hypertension involves alteration in vascular resistance caused by sympathetic nervous system (SNS) and renin angiotensin system (RAS). Susceptibility factors of hypertension vary with regions and ethnicities. In this study, we conducted target capture...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to China
Share to Hypertension
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Interaction Maps

Source

Open in PubMed Open full text

Identifiers

PMID: 34297769
DOI: 10.1371/journal.pone.0255311
PMCID: PMC8301621

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeted capture sequencing identifies genetic variations of GRK4 and RDH8 in Han Chinese with essential hypertension in Xinjiang.PMID 34297769Read ↗

Resistant Hypertension Variants Link to Hyperaldosteronism and Potassium Levels.Semantic proximity Read ↗

Longitudinal exome-wide association study to identify genetic susceptibility loci for hypertension in a Japanese population.Semantic proximity Read ↗

Genetic variation of NEDD4L is associated with essential hypertension in female Kazakh general population: a case-control study.Semantic proximity Read ↗

Detection of genetic variations of regulator of G-protein signaling 2 in hypertensives by sequencing.Semantic proximity Read ↗

Uncovering the shared genetic contributors to primary and secondary hypertension using whole genome sequencing in a national disease cohortSemantic proximity Read ↗

Common variants of the G protein-coupled receptor type 4 are associated with human essential hypertension and predict the blood pressure response to angiotensin receptor blockade.Semantic proximity Read ↗

Genome-wide Meta-analysis Reveals New Gene Signatures and Potential Drug Targets of HypertensionSemantic proximity Read ↗

Whole -genome survival analysis of 144 286 people from the UK Biobank identifies novel loci associated with blood pressure.Semantic proximity Read ↗

Identification of Novel Therapeutic Targets for Hypertension.Semantic proximity Read ↗

Replication of a genome-wide association study on essential hypertension in Mongolians.Semantic proximity Read ↗

GWAS and Replication Analysis of Apparent Treatment-Resistant Hypertension.Semantic proximity Read ↗

Association of rs2271037 and rs3749585 polymorphisms in CORIN with susceptibility to hypertension in a Chinese Han population: A case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.