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Article

Longitudinal exome-wide association study to identify genetic susceptibility loci for hypertension in a Japanese population.

Experimental & molecular medicine - 8 Dec 2017

Yasukochi Yoshiki, Sakuma Jun, Takeuchi Ichiro, Kato Kimihiko, Oguri Mitsutoshi, Fujimaki Tetsuo, Horibe Hideki, Yamada Yoshiji

Abstract excerpt

Genome-wide association studies have identified various genetic variants associated with complex disorders. However, these studies have commonly been conducted in a cross-sectional manner. Therefore, we performed a longitudinal exome-wide association study (EWAS) in a Japanese cohort. We aimed to identify genetic variants that confer susceptibility to hypertension using ~244 000 single-nucleotide variants (SNVs)...

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Identifiers

PMID: 29217820
DOI: 10.1038/emm.2017.209
PMCID: PMC5750474

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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