Article
Association of rs2271037 and rs3749585 polymorphisms in CORIN with susceptibility to hypertension in a Chinese Han population: A case-control study.
Gene - 20 Apr 2018
Chen Yan-Li, Li Tie-Jun, Hao Ying, Wu Bao-Gang, Li Hong, Geng Ning, Sun Zhao-Qing, Zheng Li-Qiang, Sun Ying-Xian
Abstract excerpt
Corins are membrane-bound protease that regulates blood pressure by activating the natriuretic peptides. These pro-atrial natriuretic peptide convertases are essential for sodium homeostasis and normal blood pressure. CORIN variants have been identified in humans and other animals, but no studies of CORIN polymorphisms have been conducted in northeastern China. This study aims to investigate the association of 2...
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