Article

Uncovering the shared genetic contributors to primary and secondary hypertension using whole genome sequencing in a national disease cohort

2024-11-20

Abstract excerpt

<h4>Introduction</h4> Extreme early-onset hypertension (EEHTN) defines a cohort of patients with a persistent blood pressure above 160/100mmHg under 30 years of age. This cohort is at heightened risk of complications and often undergo a diagnostic odyssey. We used Whole Genome Sequencing (WGS) data provided by the 100,000 Genomes Project (100KGP), to quantify the genetic contributors to EEHTN and to ascertain the...

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Literature Corpus work: 8cc093ee-70a0-5b2b-b7e9-b1fa8dff46f2
DOI: 10.1101/2024.11.20.24317623

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