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Article

Whole -genome survival analysis of 144 286 people from the UK Biobank identifies novel loci associated with blood pressure.

Journal of hypertension - 1 Sept 2024

Saluja Sushant, Darlay Rebecca, Lennon Rachel, Keavney Bernard D, Cordell Heather J

Abstract excerpt

This study utilized UK Biobank data from 144 286 participants and employed whole-genome sequencing (WGS) data and time-to-event data over a 12-year follow-up period to identify susceptibility in genetic variants associated with hypertension. Following genotype quality control, 6 319 822 single nucleotide polymorphisms underwent analysis, revealing 31 significant variant-level associations. Among these, 29 were...

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Identifiers

PMID: 39011893
DOI: 10.1097/HJH.0000000000003801
PMCID: PMC11296269

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