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Increased gene expression variability in BRCA1-associated and basal-like breast tumours.

Breast cancer research and treatment - 1 Sept 2021

Wiggins George A R, Black Michael A, Dunbier Anita, Morley-Bunker Arthur E, Pearson John F, Walker Logan C

Abstract excerpt

PURPOSE: Inherited variants in the cancer susceptibility genes, BRCA1 and BRCA2 account for up to 5% of breast cancers. Multiple gene expression studies have analysed gene expression patterns that maybe associated with BRCA12 pathogenic variant status; however, results from these studies lack consensus. These studies have focused on the differences in population means to identified genes associated with...

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Identifiers

PMID: 34287743
DOI: 10.1007/s10549-021-06328-y
PMCID: PMC8357684

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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