Article
A pan-cancer analysis of alternative splicing of splicing factors in 6904 patients.
Oncogene - 1 Sept 2021
Cheng Rui, Xiao Lixing, Zhou Wenyang, Jin Xiyun, Xu Zhaochun, Xu Chang, Wang Pingping, Luo Meng, Wang Mengyun, Ma Kexin, Cao Huimin, Huang Yan, Lin Xiaoyu, Pang Fenglan, Li Yiqun, Jiang Qinghua
Abstract excerpt
Great progress has been made in the investigation on mutation and expression of splicing factor. However, little is known on the role of alternative splicing of splicing factors across cancers. Here, we reported a pan-cancer analysis of alternative splicing of splicing factors spanning 6904 patients across 16 cancer types, and identified 167 splicing factors with implications regulating cancer-specific splicing...
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