Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Splicing-factor alterations in cancers

16 Aug 2016

Abstract excerpt

Tumor-associated alterations in RNA splicing result either from mutations in splicing-regulatory elements or changes in components of the splicing machinery. This review summarizes our current understanding of the role of splicing-factor alterations in human cancers. We describe splicing-factor alterations detected in human tumors and the resulting changes in splicing, highlighting cell-type-specific similarities...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurogenetic and Muscular Disorders Research
Share to RNA modifications and cancer
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27530828
DOI: 10.1261/rna.057919.116

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Splicing-factor alterations in cancersPMID 27530828Read ↗

Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes.Semantic proximity Read ↗

SnapShot: Splicing Alterations in Cancer.Semantic proximity Read ↗

Targeting splicing abnormalities in cancer.Semantic proximity Read ↗

Aberrant RNA splicing and therapeutic opportunities in cancers.Semantic proximity Read ↗

Splicing dysregulation in cancer: from mechanistic understanding to a new class of therapeutic targets.Semantic proximity Read ↗

Alternative splicing: an emerging topic in molecular and clinical oncology.Semantic proximity Read ↗

Splicing dysregulation in human hematologic malignancies: beyond splicing mutations.Semantic proximity Read ↗

RNA splicing factors in normal hematopoiesis and hematologic malignancies: novel therapeutic targets and strategies.Semantic proximity Read ↗

Pre-mRNA splicing aberrations and cancer.Semantic proximity Read ↗

RNA Splicing and Cancer.Semantic proximity Read ↗

A pan-cancer analysis of alternative splicing of splicing factors in 6904 patients.Semantic proximity Read ↗

Exploiting differential RNA splicing patterns: a potential new group of therapeutic targets in cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.