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Enzyme Kinetics of Uridine Diphosphate Glucuronosyltransferases (UGTs).

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Zhou Jin, Argikar Upendra A, Miners John O

Abstract excerpt

Glucuronidation, catalyzed by uridine diphosphate glucuronosyltransferases (UGTs), is an important process for the metabolism and clearance of many lipophilic chemicals, including drugs, environmental chemicals, and endogenous compounds. Glucuronidation is a bisubstrate reaction that requires the aglycone and the cofactor, UDP-GlcUA. Accumulating evidence suggests that the bisubstrate reaction follows a...

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PMID: 34272700
DOI: 10.1007/978-1-0716-1554-6_12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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