Article
Quantitative analysis of UDP-glucuronosyltransferase (UGT) 1A and UGT2B expression levels in human livers.
Drug metabolism and disposition: the biological fate of chemicals - 1 Aug 2009
Izukawa Takeshi, Nakajima Miki, Fujiwara Ryoichi, Yamanaka Hiroyuki, Fukami Tatsuki, Takamiya Masataka, Aoki Yasuhiro, Ikushiro Shin-ichi, Sakaki Toshiyuki, Yokoi Tsuyoshi
Abstract excerpt
UDP-glucuronosyltransferases (UGTs) catalyze glucuronidation of a variety of xenobiotics and endobiotics. UGTs are divided into two families, UGT1 and UGT2. The purpose of this study was to estimate the absolute expression levels of each UGT isoform in human liver and to evaluate the interindivid...
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