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Article

Emergence and Spread of kelch13 Mutations Associated with Artemisinin Resistance in Plasmodium falciparum Parasites in 12 Thai Provinces from 2007 to 2016.

Antimicrobial agents and chemotherapy - 1 Apr 2018

Kobasa Theerayot, Talundzic Eldin, Sug-Aram Rungniran, Boondat Patcharida, Goldman Ira F, Lucchi Naomi W, Dharmarak Pratin, Sintasath David, Fukuda Mark, Whistler Toni, MacArthur John, Udhayakumar Venkatachalam, Prempree Preecha, Chinanonwait Nipon

Abstract excerpt

Artemisinin-based combination therapy (ACT) is the most effective and widely used treatment for uncomplicated Plasmodium falciparum malaria and is a cornerstone for malaria control and prevention globally. Resistance to artemisinin derivatives has been confirmed in the Greater Mekong Subregion (GMS) and manifests as slow parasite clearance in patients and reduced ring stage susceptibility to artemisinins in...

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Identifiers

PMID: 29378723
DOI: 10.1128/AAC.02141-17
PMCID: PMC5914000

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Source receipt: pubmed, retrieved 7 Sept 2026.

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