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Article

β-defensin 1 Gene Polymorphisms are Associated with Kidney Disease in Northwestern Mexicans with Type 2 Diabetes.

Immunological investigations - 1 Jul 2022

Ochoa-Ramirez Luis Antonio, Rodriguez Millan José, Mendoza Vázquez Luis Fernando, Díaz-Camacho Sylvia Paz, Verdugo Quiñonez Samantha Isabel, Rojas-Herrera Dulce Carolina, López Castro Martín, Prado Montes de Oca Ernesto, Velarde-Felix Jesús Salvador

Abstract excerpt

Diabetic kidney disease (DKD) is one of the more limiting complications to the quality of life of diabetes mellitus patients. Studies including cultured cells, animal models, and case-control studies highlight the role of human β-defensin-1 (hBD-1) in diabetes.This study assessed the association of hBD-1 gene (DEFB1) functional variations -52 G/A (rs1799946), -44 C/G (rs1800972) and -20 G/A (rs11362) with type 2...

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Share to beta-Defensins
Share to Case-Control Studies
Share to Diabetes Mellitus, Type 2
Share to Diabetic Nephropathies
Share to Genetic Predisposition to Disease
Share to Mexico
Share to Polymorphism, Single Nucleotide
Share to Quality of Life

Source

Identifiers

PMID: 34251960
DOI: 10.1080/08820139.2021.1948564

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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