Article
Relevance of α-defensins (HNP1-3) and defensin β-1 in diabetes.
World journal of gastroenterology - 21 Jul 2014
Németh Balázs Csaba, Várkonyi Tamás, Somogyvári Ferenc, Lengyel Csaba, Fehértemplomi Katalin, Nyiraty Szabolcs, Kempler Péter, Mándi Yvette
Abstract excerpt
AIM: To investigate the genetic background of human defensin expression in type 1 and 2 diabetes. METHODS: Associations between DEFA1/DEFA3 gene copy number polymorphism and diabetes as well as between the promoter polymorphisms of DEFB1 and diabetes were studied. The copy number variation of the DEFA1/DEFA3 genes was determined in 257 diabetic patients (117 patients with type 1 and 140 with type 2 diabetes). The...
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