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Article

Effect of SDF-1 and CXCR4 gene variants on the development of diabetic kidney disease.

International journal of medical sciences - 1 Jan 2024

Ting Ke-Hsin, Yang Po-Jen, Su Shih-Chi, Tsai Po-Yu, Yang Shun-Fa

Abstract excerpt

Diabetic kidney disease (DKD) is the gradual loss of renal function occurring in patients with diabetes. Stromal cell-derived factor-1 (SDF-1, encoded by SDF-1 gene) is a chemokine that binds to its receptor, CXCR4, to mediate many aspects of renal biology. To test the potential impact of SDF-1/CXCR4 gene variations on the risk for DKD, single-nucleotide polymorphisms (SNPs) of SDF-1/CXCR4 genes were genotyped in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39512693
DOI: 10.7150/ijms.103186
PMCID: PMC11539390

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